Musculoskeletal/Muscle, Bone, Ligament and Tendon Problems
From the Accutane Medication Guide:
Accutane may affect bones, muscles, and ligaments and cause pain in your joints or muscles. Tell your prescriber if you plan vigorous physical activity during treatment with Accutane. Tell your prescriber if you develop pain, particularly back pain or joint pain. There are reports that some patients have had stunted growth after taking Accutane for acne as directed. There are also some reports of broken bones or reduced healing of broken bones after taking Accutane for acne as directed. No one knows if taking Accutane for acne will affect your bones. If you have a broken bone, tell your provider that you are taking Accutane. Muscle weakness with or without pain can be a sign of serious muscle damage. If this happens, stop taking Accutane and call your prescriber right away.
Accutane Product Information also includes the following information on some specific Skeletal, Bone and Muscle Accutane Side Effects:
- Bone Mineral Density: "Effects of multiple courses of Accutane on the developing musculoskeletal system are unknown. Bone Mineral Density tests showed some decreases in bone mineral density." This information is included in some detail in Accutane Label Information.
- Skeletal Hyperostosis: "A high prevalence of skeletal hyperostosis was noted in clinical trials for disorders of keratinization. Minimal skeletal hyperostosis and calcification of ligaments and tendons have also been observed by x-ray in prospective studies of nodular acne patients treated with a single course of therapy at recommended doses. The skeletal effects of multiple Accutane treatment courses for acne are unknown." Skeletal hyperostosis is bony overgrowth (hyperostosis) where tendons and ligaments attach to the bone. It most often affects the spine.
- Premature Epiphyseal Closure: There are spontaneous reports of premature epiphyseal closure in acne patients. Epiphyseal plates, also known as growth plates or physis, are plates at the end of the long bones in the arms and legs in children and adolescents that determine the length and shape of these bones at maturity. The plates are not supposed to close and harden into solid bone until growth is complete. Premature closure will affect and stunt the growth of the bones.
- "Spontaneous reports of osteoporosis, osteopenia, bone fractures, and delayed healing of bone fractures have been seen in the Accutane population. While causality to Accutane has not been established, an effect cannot be ruled out." Osteopenia is milder bone density loss than osteoporosis.
- Back pain is reported in a significant percentage of those taking Accutane.
These are just some examples of the kinds of musculoskeletal (muscle, bone, tendon and ligament) problems that may develop with the use of Accutane.
For more information, visit our Musculoskeletal Disorders Resources page.
If you or a loved one has suffered from musculoskeletal (muscle, bone, tendon and ligament) problems or complications from taking Accutane, please call or e-mail today and we will evaluate your Accutane claim for free.
Call or e-mail our Accutane Claim Lawyers
Levin • Papantonio • Thomas • Mitchell • Echsner & Proctor, P.A.
316 South Baylen Street, Suite 600 • Pensacola, FL 32502-5996